Hydrohysteroid Dehydrogenases – Biological Role and Clinical Importance – Review

A review of the role and importance of essential fatty acids in the feeding of ornamental fish

Ornamental fish farming, like other aquaculture productions, it depends on the quality and quantity of egg production, hatching, fecundity and survival of the larvae. In general, every step of aquaculture, followed by nutritional goals. Most of these studies are in the stages of larval growth. Because the highest costs are imposed on aquaculture and the most critical biological period of orname...

Clinical implications of glucocorticoid metabolism by 11beta-hydroxysteroid dehydrogenases in target tissues.

11beta-Hydroxysteroid dehydrogenases (11beta-HSD) are microsomal enzymes that catalyze the conversion of active glucocorticoids (GC) to their inactive 11-dehydro products and vice versa. Two isoenzymes of 11beta-HSD have been characterized and cloned in human tissues. The tissue-specific metabolism of GC by these enzymes is important for mineralocorticoid (MC) and GC receptor occupancy and seem...

New Aspects of Bilirubin Effects in Health and Disease: a Review

Bilirubin belongs to a phylogenetically old superfamily of tetrapyrrolic compounds. Although for decades bilirubin was believed to be only a waste product of the heme catabolic pathway and a potentially toxic compound; recent data has convincingly demonstrated that mildly elevated serum bilirubin levels are strongly associated with a lower prevalence of oxidative stress-mediated diseases, such ...

Water Stress Induces the Up-regulation of a Specific Set of Genes in Plants: Aldehyde Dehydrogenases as an Example

The deleterious effect of osmotic stress is often caused by the accumulation of reactive molecules e.g. aldehydes. These molecules can cause lipid peroxidation and modifications of proteins and nucleic acids. Aldehydes can be converted to non-toxic carboxylic acids by different aldehyde dehydrogenases (ALDH). ALDHs occur in all organisms implicating their importance in general biological functi...

Alpha, beta-dehydrogenation by acyl-CoA dehydrogenases: role of functional groups at the active center.